4 edition of Toxicology of the liver found in the catalog.
Includes bibliographical references and index.
|Statement||editors, Gabriel L. Plaa, William R. Hewitt.|
|Series||Target organ toxicology series|
|Contributions||Plaa, Gabriel L., Hewitt, William R.|
|LC Classifications||RC848.H48 T69 1998|
|The Physical Object|
|Pagination||xi, 431 p. :|
|Number of Pages||431|
|LC Control Number||97022577|
Hepatotoxicity implies chemical-driven liver damage. Drug-induced liver injury is a cause of acute and chronic liver disease. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Certain medicinal agents, when taken in overdoses and sometimes even when introduced within therapeutic ranges, may injure the organ. Other chemical Specialty: Gastroenterology. The liver’s strategic location between intestinal tract and the rest of the body facilitates the performance of its enormous task of maintaining the metabolic homeostasis of the body. Venous blood from the stomach and intestines flows into the portal vein, through the liver.
Common Characteristics of Toxicity Double action Local: irritation of the GIT mucosa/respiratory epithelium. Remote: Parenchymatous organs such as liver, kidneys and heart. Symptoms and signs appear after a latent period following exposure. Cumulative toxic effect: acute and chronic forms of toxicity. Great affinity to keratin tissues. Separate registration required. Course Book. Room Chairperson(s): Weida Tong, US FDA, National Center for Toxicological Research; and Richard Paules, NTP/NIEHS. Toxicology in the 21st century is marked with increasing incorporation of high throughput technologies to improve our molecular-level understanding of toxicity, moving towards a data-driven regulatory decision-making paradigm.
most!basic!challenges!of!toxicology:!is!it!the!quantity!of!the!toxin!or!the! makeUupof!the!person?!! Forensic!toxicologyapplies!analytical!toxicologytothepurposes!of. Drs. Busuttil and Klintmalm present Transplantation of the Liver, 3 rd Edition, which has been thoroughly revised to offer you the latest protocols, surgical approaches, and techniques used in this challenging procedure. Encompassing today's expert knowledge in the field, this medical reference book is an ideal single source for authoritative, up-to-date guidance on every imaginable aspect of Format: Book.
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Toxicology of the Liver. DOI link for Toxicology of the Liver. Toxicology of the Liver book. Toxicology of the Liver. DOI link for Toxicology of the Liver. Toxicology of the Liver book.
Edited By Gabriel L Plaa, WR Hewitt. Edition 2nd Edition. Cited by: Toxicology of the Liver (Target Organ Toxicology Series) [Plaa, Gabriel L, Hewitt, WR] on *FREE* shipping on qualifying offers. Toxicology of the Liver (Target Organ Toxicology Author: Gabriel L Plaa.
ISBN: OCLC Number: Description: xii, pages: illustrations ; 24 cm. Series Title: Target organ toxicology series. COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.
Liver Toxicology. The liver is a vital organ with many crucial functions. Importantly, it Toxicology of the liver book the principal site for the metabolism of drugs and other xenobiotics. Many such chemicals can damage hepatocytes, the major cell type in the liver; in fact, liver injury is the chief reason for the withdrawal of a.
Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases.
It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants.
Doxorubicin and its analogues are metabolized in the liver via microsomal enzymes, and production of a toxic or immunogenic intermediate may trigger liver injury.
Outcome and Management The severity of the liver injury linked to doxorubicin, epirubicin and idarubicin therapy is usually mild and self-limited.
Discover the best Toxicology in Best Sellers. Find the top most popular items in Amazon Books Best Sellers. Fatty Liver:The Natural Fatty Liver Cure, Proven Strategies to Reverse, Cure and Prevent Fatty Liver Forever. Essential Hand Book of Toxicology Izharul Hasan. Kindle Edition. This book covers a range of core toxicological areas, including pesticides, radioactive materials and poisonous plants, also presenting a section on veterinary toxicology.
Across 16 chapters, the book presents key concepts with the aid of over detailed, full-color illustrations. Buy Toxicology of the Liver by Gabriel L Plaa (Editor), Wr Hewitt (Editor) online at Alibris.
We have new and used copies available, in 2 editions - starting at $ Shop now. Veterinary Toxicology, Basic and Clinical Principles, Third Edition, is a unique, single reference that teaches the basic principles of veterinary toxicology to any student at the DVM, MS or PhD level.
Valerian is a botanical extract derived from the roots of Valeriana officinalis, which is widely used in herbal medicine for insomnia, anxiety and digestive and urinary problems. Valerian has been linked to rare instances of clinically apparent liver injury.
This book provides a comprehensive view of the methodologies used for the study of liver toxicity encountered throughout the whole life cycle of a drug, from drug discovery, to clinical trial, post-marketing, and even clinical practice.
Physiologically relevant models for drug toxicity screening and safety testing. Our 3D toxicology experts understand which assays and endpoints will best help you assess toxicity risk early in the drug discovery and development process.
You can rely on our certified applications for preclinical drug safety to better approximate human to compound dosing and conduct revealing translational and. Toxicology describes the adverse and, in the worst case, lethal effects of substances on tissues, organs, organisms, and even on systems of higher complexity.
However, these effects are the outcome of damage to single cells, which results in loss of the cell's specific function for a. INTRODUCTION. The liver performs many functions that are critical to life.
Among these are the processing of foods and other substances absorbed from the intestinal tract and the subsequent delivery of processed nutrients to other organs in the body.
The liver is also an integral contributor of immunity that protects mammals from harmful pathogens. Introduction. The liver is the main organ where exogenous chemicals are metabolized and eventually excreted.
As a consequence, liver cells are exposed to significant concentrations of these chemicals, which can result in liver dysfunction, cell injury, and even organ failure.
If an industrial chemical, for example carbon tetrachloride, bromobenzene. Toxicology is an international, peer-reviewed journal that publishes only the highest quality original scientific research and critical reviews describing hypothesis-based investigations into mechanisms of toxicity associated with exposures to xenobiotic chemicals, particularly as it relates to human health.
In this respect "mechanisms" is defined on both the macro (e.g. physiological. Overdose and poisoning are one of the most frequent acute medical presentations seen in emergency departments, and high dependency and intensive care facilities.
The Oxford Desk Reference: Toxicology provides an authoritative guide for the management of patients with poisoning. Each chapter includes key clinical features and potential treatment options to help physicians to assess the. This comprehensive volume discusses the various classes of toxic substances found in plants, and includes a series of monographs on specific species.
Filled with figures and illustrations, this important reference presents information on clinical effects, the various common and botanic names, specific or class of toxin, case reports, mechanism of action, and risk assessment.
This section contains free e-books and guides on toxicology, some of the resources in this section can be viewed online and some of them can be downloaded. Principles of Toxicology. Toxicology studies the injurious effects of chemical and physical agents on living organisms, observed as alterations in structure and covered.The Toxicology of Glycol Ethers and its Relevance to Man ECETOC TR No.
95 Measurement methods 56 Health effects 59 Haematological effects 60 Behavioural and neurological effects 62 Reproductive effects 63 Other effects, including poisoning 67 Occupational exposure limit values 72File Size: KB.A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the : Tahar Abdulaziz Suliman.